Antibiotic resistance of emerging pathogenic bacteria of hybrid grouper farming in Indonesia

Abstract. Istiqomah I, Isnansetyo A, Murwantoko, Handayani DP, Lestari YN, Taslihan Permana IGN, Wijayanti E. 2023. Antibiotic resistance of emerging pathogenic bacteria hybrid grouper farming in Indonesia. Biodiversitas 24: 2493-2501. A is among the main coastal species Asian countries, yet vibriosis still a significant issue. Therefore, knowledge strains responsible for recent cases essential developing appropriate control measures. The purpose study was to describe bacterial pathogens associated with hemorrhagic disorder, skin wounds, and mortality cantang farms total 30 were recovered from kidney diseased on TCBS agar. Based ability induce clinical signs juveniles owing intraperitoneal infection at 106 CFU/fish, divided into three groups: (n=11), low-pathogenic (n=2), non-pathogenic (n=17). putatively identified as Photobacterium damselae subsp. Damselae (n=8), Vibrio alginolyticus (n=1), harveyi azureus (n=2) based biochemical characteristics 16S rRNA DNA gyrase B subunit gene sequences. sensitive erythromycin, gentamycin, oxytetracycline, kanamycin. However, it has various resistant patterns ampicillin, fosfomycin, chloramphenicol, streptomycin, rifampicin, enrofloxacin. This demonstrated emergence P. damselae, alginolyticus, V. harveyi, aquaculture Indonesia multiple antibiotic resistance, which needed further studies.